Immobilization of Active Compounds and Microorganisms

Immobilization of Active Compounds and Microorganisms

Immobilization of active compounds and living microorganisms is a powerful strategy with a wide range of applications across biotechnology, environmental science, and medicine. This approach involves fixing microorganisms, such as bacteria, fungi, and algae, onto solid surfaces or within matrices, enabling continuous activity in processes like resource recovery, pollutant degradation, and bioremediation. Additionally, immobilized microorganisms are used in the development of microbial fuel cells for power generation, as well as in biosensors for environmental monitoring.

Furthermore, biofunctionalization of material surfaces through the integration of bioactive compounds and biomolecules opens up possibilities in artificial biofilm formation and the development of innovative systems for ecological applications, such as moss and mycorrhizal fungi for facade and roof greening. Immobilization techniques also enhance the functionality of antimicrobial substances in medical devices, textiles, and packaging, contributing to sterilization, disinfection, and controlled drug release for therapeutic purposes.

The innovation area “Immobilization of active compounds and microorganisms” at the Department Dresden – “Functional Coatings” encompasses a wide range of applications across various fields. The following list highlights some of the key areas where this technology is being applied, demonstrating its versatility in sectors such as environmental remediation, bioenergy production, medical treatments, and more.

  • Immobilization of living microorganisms (bacteria, fungi & algae)
    • Cultivation of microorganisms for resource recovery
    • Degradation of pollutants / bioremediation
    • Microbial fuel cells for power generation
    • Immobilization of mycorrhizal fungi to promote plant growth
    • Biosensor applications
  • Biofunctionalization of Material Surfaces
    • Integration of bioactive compounds and biomolecules
    • Artificial biofilm formation
    • Immobilization of mosses and mycorrhizal fungi for facade and roof greening
  • Integration of Antimicrobial Substances
    • Antimicrobial coating of medical disposable products (catheters, drains, wound dressings)
    • Sterilization & disinfection of (food) packaging
    • Functionalization of textiles
  • Therapeutic Applications
    • Coating and functionalization of medical disposable products
    • Immobilization and controlled release of essential oils
    • Controlled drug release